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Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver

Phosphatases of regenerating liver (PRL or PTP4A) are a family of enigmatic protein phosphatases implicated in cell growth and metabolism. Despite their relevance in metastatic cancer, much remains unknown about the PRL family. They act as pseudophosphatases to regulate the CNNM family of magnesium...

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Detalles Bibliográficos
Autores principales: Fakih, Rayan, Goldstein, Robert H., Kozlov, Guennadi, Gehring, Kalle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040874/
https://www.ncbi.nlm.nih.gov/pubmed/36822330
http://dx.doi.org/10.1016/j.jbc.2023.103055