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Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules

COVID-19 has seriously threatened public health, and transdermal vaccination is an effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum corneum to allow passive diffusion of vaccine macromolecules, but the delivery efficiency is low, while iontophoresis can actively...

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Detalles Bibliográficos
Autores principales: Zheng, Ying, Ye, Rui, Gong, Xia, Yang, Jingbo, Liu, Bin, Xu, Yunsheng, Nie, Gang, Xie, Xi, Jiang, Lelun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040928/
https://www.ncbi.nlm.nih.gov/pubmed/36987502
http://dx.doi.org/10.1038/s41378-023-00515-1