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Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules
COVID-19 has seriously threatened public health, and transdermal vaccination is an effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum corneum to allow passive diffusion of vaccine macromolecules, but the delivery efficiency is low, while iontophoresis can actively...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040928/ https://www.ncbi.nlm.nih.gov/pubmed/36987502 http://dx.doi.org/10.1038/s41378-023-00515-1 |