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A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with the unique ability to mediate inflammatory responses of the immune system. Given the critical role of DCs in shaping immunity, they present an attractive avenue as a therapeutic target to program the immune system and revers...

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Detalles Bibliográficos
Autores principales: Aghamiri, Sara Sadat, Puniya, Bhanwar Lal, Amin, Rada, Helikar, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040975/
https://www.ncbi.nlm.nih.gov/pubmed/36993954
http://dx.doi.org/10.3389/fimmu.2023.1112985