Dysregulation of ribosome-associated quality control elicits cognitive disorders via overaccumulation of TTC3

Ribosome-associated quality control (RQC) pathway is responsible for degradation of nascent polypeptides in aberrantly stalled ribosomes, and its defects may lead to neurological diseases. However, the underlying molecular mechanism of how RQC dysfunction elicits neurological disorders remains poorl...

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Detalles Bibliográficos
Autores principales: Endo, Ryo, Chen, Yi-Kai, Burke, John, Takashima, Noriko, Suryawanshi, Nayan, Hui, Kelvin K., Miyazaki, Tatsuhiko, Tanaka, Motomasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041068/
https://www.ncbi.nlm.nih.gov/pubmed/36917672
http://dx.doi.org/10.1073/pnas.2211522120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041068/
https://www.ncbi.nlm.nih.gov/pubmed/36917672
http://dx.doi.org/10.1073/pnas.2211522120

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