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Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores

Alphaviruses are emerging positive-stranded RNA viruses which replicate and transcribe their genomes in membranous organelles formed in the cell cytoplasm. The nonstructural protein 1 (nsP1) is responsible for viral RNA capping and gates the replication organelles by assembling into monotopic membra...

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Detalles Bibliográficos
Autores principales: Jones, Rhian, Hons, Michael, Rabah, Nadia, Zamarreño, Noelia, Arranz, Rocío, Reguera, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041110/
https://www.ncbi.nlm.nih.gov/pubmed/36913573
http://dx.doi.org/10.1073/pnas.2213934120