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Chronic CD27-CD70 costimulation promotes type 1-specific polarization of effector Tregs
INTRODUCTION: Most T lymphocytes, including regulatory T cells, express the CD27 costimulatory receptor in steady state conditions. There is evidence that CD27 engagement on conventional T lymphocytes favors the development of Th1 and cytotoxic responses in mice and humans, but the impact on the reg...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041113/ https://www.ncbi.nlm.nih.gov/pubmed/36993956 http://dx.doi.org/10.3389/fimmu.2023.1023064 |