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Chronic CD27-CD70 costimulation promotes type 1-specific polarization of effector Tregs

INTRODUCTION: Most T lymphocytes, including regulatory T cells, express the CD27 costimulatory receptor in steady state conditions. There is evidence that CD27 engagement on conventional T lymphocytes favors the development of Th1 and cytotoxic responses in mice and humans, but the impact on the reg...

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Detalles Bibliográficos
Autores principales: Bowakim-Anta, Natalia, Acolty, Valérie, Azouz, Abdulkader, Yagita, Hideo, Leo, Oberdan, Goriely, Stanislas, Oldenhove, Guillaume, Moser, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041113/
https://www.ncbi.nlm.nih.gov/pubmed/36993956
http://dx.doi.org/10.3389/fimmu.2023.1023064