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Learning critically drives parkinsonian motor deficits through imbalanced striatal pathway recruitment
Dopamine (DA) loss in Parkinson’s disease (PD) causes debilitating motor deficits. However, dopamine is also widely linked to reward prediction and learning, and the contribution of dopamine-dependent learning to movements that are impaired in PD—which often do not lead to explicit rewards—is unclea...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041136/ https://www.ncbi.nlm.nih.gov/pubmed/36920928 http://dx.doi.org/10.1073/pnas.2213093120 |