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Stress keratin 17 and estrogen support viral persistence and modulate the immune environment during cervicovaginal murine papillomavirus infection

A murine papillomavirus, MmuPV1, infects both cutaneous and mucosal epithelia of laboratory mice and can be used to model high-risk human papillomavirus (HPV) infection and HPV-associated disease. We have shown that estrogen exacerbates papillomavirus-induced cervical disease in HPV-transgenic mice....

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Detalles Bibliográficos
Autores principales: Wang, Wei, Spurgeon, Megan E., Pope, Ali, McGregor, Stephanie, Ward-Shaw, Ella, Gronski, Ellery, Lambert, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041145/
https://www.ncbi.nlm.nih.gov/pubmed/36917668
http://dx.doi.org/10.1073/pnas.2214225120