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Fragile X mental retardation protein coordinates neuron-to-glia communication for clearance of developmentally transient brain neurons
In the developmental remodeling of brain circuits, neurons are removed by glial phagocytosis to optimize adult behavior. Fragile X mental retardation protein (FMRP) regulates neuron-to-glia signaling to drive glial phagocytosis for targeted neuron pruning. We find that FMRP acts in a mothers against...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041173/ https://www.ncbi.nlm.nih.gov/pubmed/36920921 http://dx.doi.org/10.1073/pnas.2216887120 |