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Dynamic loading leads to increased metabolic activity and spatial redistribution of viable cell density in nucleus pulposus tissue

BACKGROUND: Nucleus pulposus (NP) cell density is orchestrated by an interplay between nutrient supply and metabolite accumulation. Physiological loading is essential for tissue homeostasis. However, dynamic loading is also believed to increase metabolic activity and could thereby interfere with cel...

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Detalles Bibliográficos
Autores principales: Salzer, Elias, Mouser, Vivian H. M., Bulsink, Jurgen A., Tryfonidou, Marianna A., Ito, Keita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041377/
https://www.ncbi.nlm.nih.gov/pubmed/36994465
http://dx.doi.org/10.1002/jsp2.1240