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Tetrahydrocurcumin Add‐On therapy to losartan in a rat model of diabetic nephropathy decreases blood pressure and markers of kidney injury

Tetrahydrocurcumin (THC), a principal metabolite of curcumin, was tested in a rat model of type 2 diabetes mellitus. THC was administered via daily oral gavage with the lipid carrier polyenylphosphatidylcholine (PPC) as add‐on therapy to losartan (angiotensin receptor blocker) to examine effects on...

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Detalles Bibliográficos
Autores principales: Khazaeli, Mahyar, Nunes, Ane C. F., Zhao, Yitong, Khazaeli, Mahziar, Prudente, John, Vaziri, Nosratola D., Singh, Bhupinder, Lau, Wei Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041385/
https://www.ncbi.nlm.nih.gov/pubmed/36971089
http://dx.doi.org/10.1002/prp2.1079