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miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy

BACKGROUND: Synucleinopathies are disorders characterized by the abnormal accumulation of α-synuclein (aSyn). Synaptic compromise is observed in synucleinopathies parallel to aSyn aggregation and is accompanied by transcript deregulation. OBJECTIVE: We sought to identify microRNAs associated with sy...

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Detalles Bibliográficos
Autores principales: Xylaki, Mary, Paiva, Isabel, Al-Azzani, Mohammed, Gerhardt, Ellen, Jain, Gaurav, Islam, Md Rezaul, Vasili, Eftychia, Wassouf, Zinah, Schulze-Hentrich, Julia M., Fischer, André, Outeiro, Tiago Fleming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041420/
https://www.ncbi.nlm.nih.gov/pubmed/36744345
http://dx.doi.org/10.3233/JPD-225055