Specific Detection of Physiological S129 Phosphorylated α-Synuclein in Tissue Using Proximity Ligation Assay

BACKGROUND: Synucleinopathies are a group of neurodegenerative disorders that are pathologically characterized by intracellular aggregates called Lewy bodies. Lewy bodies are primarily composed of α-synuclein (asyn) protein, which is mostly phosphorylated at serine 129 (pS129) when aggregated and th...

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Detalles Bibliográficos
Autores principales: Arlinghaus, Ryan, Iba, Michiyo, Masliah, Eliezer, Cookson, Mark R., Landeck, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041430/
https://www.ncbi.nlm.nih.gov/pubmed/36847016
http://dx.doi.org/10.3233/JPD-213085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041430/
https://www.ncbi.nlm.nih.gov/pubmed/36847016
http://dx.doi.org/10.3233/JPD-213085

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