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Specific Detection of Physiological S129 Phosphorylated α-Synuclein in Tissue Using Proximity Ligation Assay

BACKGROUND: Synucleinopathies are a group of neurodegenerative disorders that are pathologically characterized by intracellular aggregates called Lewy bodies. Lewy bodies are primarily composed of α-synuclein (asyn) protein, which is mostly phosphorylated at serine 129 (pS129) when aggregated and th...

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Detalles Bibliográficos
Autores principales:	Arlinghaus, Ryan, Iba, Michiyo, Masliah, Eliezer, Cookson, Mark R., Landeck, Natalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2023
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041430/ https://www.ncbi.nlm.nih.gov/pubmed/36847016 http://dx.doi.org/10.3233/JPD-213085

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