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Plasma Glial Fibrillary Acidic Protein Is Associated with (18)F-SMBT-1 PET: Two Putative Astrocyte Reactivity Biomarkers for Alzheimer’s Disease

BACKGROUND: Astrocyte reactivity is an early event along the Alzheimer’s disease (AD) continuum. Plasma glial fibrillary acidic protein (GFAP), posited to reflect astrocyte reactivity, is elevated across the AD continuum from preclinical to dementia stages. Monoamine oxidase-B (MAO-B) is also elevat...

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Detalles Bibliográficos
Autores principales: Chatterjee, Pratishtha, Doré, Vincent, Pedrini, Steve, Krishnadas, Natasha, Thota, Rohith, Bourgeat, Pierrick, Ikonomovic, Milos D., Rainey-Smith, Stephanie R., Burnham, Samantha C., Fowler, Christopher, Taddei, Kevin, Mulligan, Rachel, Ames, David, Masters, Colin L., Fripp, Jürgen, Rowe, Christopher C., Martins, Ralph N., Villemagne, Victor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041433/
https://www.ncbi.nlm.nih.gov/pubmed/36776057
http://dx.doi.org/10.3233/JAD-220908