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Process intensification for lentiviral vector manufacturing using tangential flow depth filtration

For gene therapies to become more accessible and affordable treatment options, process intensification is one possible strategy to increase the number of doses generated per batch of viral vector. Process intensification for lentiviral vector manufacturing can be achieved by enabling perfusion in th...

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Detalles Bibliográficos
Autores principales: Tona, Robert M., Shah, Reeti, Middaugh, Kimberly, Steve, Justin, Marques, João, Roszell, Blair R., Jung, Cindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041461/
https://www.ncbi.nlm.nih.gov/pubmed/36994313
http://dx.doi.org/10.1016/j.omtm.2023.02.017