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Nucleotide metabolism: a pan-cancer metabolic dependency

Metabolic alterations are a key hallmark of cancer cells, and the augmented synthesis and use of nucleotide triphosphates is a critical and universal metabolic dependency of cancer cells across different cancer types and genetic backgrounds. Many of the aggressive behaviours of cancer cells, includi...

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Detalles Bibliográficos
Autores principales: Mullen, Nicholas J., Singh, Pankaj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041518/
https://www.ncbi.nlm.nih.gov/pubmed/36973407
http://dx.doi.org/10.1038/s41568-023-00557-7