Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4′-piperidin]-1′-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of σ Receptors via Fluorescence-Based Techniques

[Image: see text] Sigma (σ) receptor subtypes, σ(1) and σ(2), are targets of wide pharmaceutical interest. The σ(2) receptor holds promise for the development of diagnostics and therapeutics against cancer and Alzheimer’s disease. Nevertheless, little is known about the mechanisms activated by the σ...

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Detalles Bibliográficos
Autores principales: Abatematteo, Francesca Serena, Majellaro, Maria, Montsch, Bianca, Prieto-Díaz, Rubén, Niso, Mauro, Contino, Marialessandra, Stefanachi, Angela, Riganti, Chiara, Mangiatordi, Giuseppe Felice, Delre, Pietro, Heffeter, Petra, Sotelo, Eddy, Abate, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041534/
https://www.ncbi.nlm.nih.gov/pubmed/36919956
http://dx.doi.org/10.1021/acs.jmedchem.2c01227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041534/
https://www.ncbi.nlm.nih.gov/pubmed/36919956
http://dx.doi.org/10.1021/acs.jmedchem.2c01227

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