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NRF1 Regulates the Epithelial Mesenchymal Transition of Breast Cancer by Modulating ROS Homeostasis

Introduction: Nuclear respiratory factor 1 (NRF1) is an important regulator involved in mitochondrial biogenesis and energy metabolism. However, the specific mechanism of NRF1 in anoikis and epithelial-mesenchymal transition (EMT) remains unclear. Methods: We examined the effect of NRF1 on mitochond...

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Detalles Bibliográficos
Autores principales: Sun, Linjuan, Ouyang, Nan, Shafi, Shaheryar, Zhao, Rongchuan, Pan, Jinlin, Hong, Lei, Song, Xueyan, Sa, Xiaohan, Zhou, Yuanshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041595/
https://www.ncbi.nlm.nih.gov/pubmed/36960492
http://dx.doi.org/10.1177/15330338231161141