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FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation

BACKGROUND: Fucosyltransferase 2(FUT2) and its induced α-1,2 fucosylation is associated with cancer metastasis. However, the role of FUT2 in colorectal cancer (CRC) metastasis remains unclear. METHODS: The expression levels and clinical analyses of FUT2 were assessed in CRC samples. Migration and in...

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Detalles Bibliográficos
Autores principales: He, Lingnan, Guo, Zijun, Wang, Weijun, Tian, Shuxin, Lin, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041739/
https://www.ncbi.nlm.nih.gov/pubmed/36973740
http://dx.doi.org/10.1186/s12964-023-01060-0