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Tumor-targeted superantigens produce curative tumor immunity with induction of memory and demonstrated antigen spreading

BACKGROUND: Despite remarkable progress, the immunotherapies currently used in the clinic, such as immune checkpoint blockade (ICB) therapy, still have limited efficacy against many types of solid tumors. One major barrier to effective treatment is the lack of a durable long-term response. Tumor-tar...

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Detalles Bibliográficos
Autores principales: Azulay, Meir, Shahar, Michal, Shany, Eitan, Elbaz, Eti, Lifshits, Sveta, Törngren, Marie, Friedmann, Adam, Kramer, Robert, Hedlund, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041807/
https://www.ncbi.nlm.nih.gov/pubmed/36967382
http://dx.doi.org/10.1186/s12967-023-04064-z