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Tumor-targeted superantigens produce curative tumor immunity with induction of memory and demonstrated antigen spreading
BACKGROUND: Despite remarkable progress, the immunotherapies currently used in the clinic, such as immune checkpoint blockade (ICB) therapy, still have limited efficacy against many types of solid tumors. One major barrier to effective treatment is the lack of a durable long-term response. Tumor-tar...
Autores principales: | Azulay, Meir, Shahar, Michal, Shany, Eitan, Elbaz, Eti, Lifshits, Sveta, Törngren, Marie, Friedmann, Adam, Kramer, Robert, Hedlund, Gunnar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041807/ https://www.ncbi.nlm.nih.gov/pubmed/36967382 http://dx.doi.org/10.1186/s12967-023-04064-z |
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