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Challenges of using historical data in clinical trials
Clinical trials’ attempts to improve design and analysis in order to reduce the experimental burden, providing more rapid and valid answers, are common, especially in rare or pediatric diseases, or in the setting of an emerging disease such as COVID-19. One promising though underused approach is to...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier Masson SAS
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041886/ http://dx.doi.org/10.1016/j.respe.2021.04.017 |