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Characterizing the top-down sequencing of protein ions prior to mobility separation in a timsTOF

Mass spectrometry (MS)-based proteomics workflows of intact protein ions have increasingly been utilized to study biological systems. These workflows, however, frequently result in convoluted and difficult to analyze mass spectra. Ion mobility spectrometry (IMS) is a promising tool to overcome these...

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Detalles Bibliográficos
Autores principales: Graham, Katherine A., Lawlor, Charles F., Borotto, Nicholas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042122/
https://www.ncbi.nlm.nih.gov/pubmed/36876327
http://dx.doi.org/10.1039/d2an01682f