Bone marrow stromal cell‐derived exosomes improve oxidative stress and pyroptosis in doxorubicin‐induced myocardial injury in vitro by regulating the transcription of GSDMD through the PI3K‐AKT‐Foxo1 pathway

OBJECTIVES: Doxorubicin (DOX) can contribute to severe myocardial injury, and bone marrow stromal cells (BMSC)‐exosomes (Exos) improves acute myocardial infarction. Hence, this research investigated whether BMSC‐Exos alleviated DOX‐induced myocardial injury. METHODS: BMSC‐derived Exos were isolated...

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Detalles Bibliográficos
Autores principales: Zeng, Hong, Yang, Yong, Tou, Fangfang, Zhan, Yuliang, Liu, Songtao, Zou, Pengtao, Chen, Yanmei, Shao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042126/
https://www.ncbi.nlm.nih.gov/pubmed/36988259
http://dx.doi.org/10.1002/iid3.810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042126/
https://www.ncbi.nlm.nih.gov/pubmed/36988259
http://dx.doi.org/10.1002/iid3.810

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