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Synthesis and Biological Evaluation of Gentiopicroside Derivatives as Novel Cyclooxygenase-2 Inhibitors with Anti-Inflammatory Activity

PURPOSE: Nonsteroidal anti-inflammatory drugs cause a series of adverse reactions. Thus, the search for new cyclooxygenase-2 selective inhibitors have become the main direction of research on anti-inflammatory drugs. Gentiopicroside is a novel selective inhibitor of cyclooxygenase-2 from Chinese her...

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Detalles Bibliográficos
Autores principales: Ren, Guojin, Zhang, Qili, Xia, Pengfei, Wang, Jie, Fang, Pengxia, Jin, Xiaojie, Peng, Xuejing, Xu, Yanli, Zhang, Jian, Zhao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042259/
https://www.ncbi.nlm.nih.gov/pubmed/36992901
http://dx.doi.org/10.2147/DDDT.S398861