Analysis of gene expression and use of connectivity mapping to identify drugs for treatment of human glomerulopathies

BACKGROUND: Human glomerulonephritis (GN)—membranous nephropathy (MN), focal segmental glomerulosclerosis (FSGS) and IgA nephropathy (IgAN), as well as diabetic nephropathy (DN) are leading causes of chronic kidney disease. In these glomerulopathies, distinct stimuli disrupt metabolic pathways in gl...

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Detalles Bibliográficos
Autores principales: Chung, Chen-Fang, Papillon, Joan, Navarro-Betancourt, José R., Guillemette, Julie, Bhope, Ameya, Emad, Amin, Cybulsky, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042326/
https://www.ncbi.nlm.nih.gov/pubmed/36993805
http://dx.doi.org/10.3389/fmed.2023.1122328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042326/
https://www.ncbi.nlm.nih.gov/pubmed/36993805
http://dx.doi.org/10.3389/fmed.2023.1122328

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