Increased hepatic interleukin-1, arachidonic acid, and reactive oxygen species mediate the protective potential of peptides shared by gut cysteine peptidases against Schistosoma mansoni infection in mice

BACKGROUND: Multiple antigen peptide (MAP) construct of peptide with high homology to Schistosoma mansoni cathepsin B1, MAP-1, and to cathepsins of the L family, MAP-2, consistently induced significant (P < 0.05) reduction in challenge S. mansoni worm burden. It was, however, necessary to modify...

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Detalles Bibliográficos
Autores principales: Tallima, Hatem, El Ridi, Rashika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042345/
https://www.ncbi.nlm.nih.gov/pubmed/36920999
http://dx.doi.org/10.1371/journal.pntd.0011164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042345/
https://www.ncbi.nlm.nih.gov/pubmed/36920999
http://dx.doi.org/10.1371/journal.pntd.0011164

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