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Construction of live-attenuated Trueperella pyogenes by antibiotic treatment and sequential passage: methods for vaccine development
Trueperella pyogenes (T. pyogenes) is a zoonotic pathogen that is cause a variety of pyogenic diseases in animals. The complex pathogenicity and various virulence factors are important challenges to produce an effective vaccine. According to previous trials, inactivated whole-cell bacteria or recomb...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042400/ https://www.ncbi.nlm.nih.gov/pubmed/36973450 http://dx.doi.org/10.1007/s00203-023-03481-4 |