Increased NLRP3 Inflammasome Activation and Pyroptosis in Patients With Multiple Sclerosis With Fingolimod Treatment Failure

BACKGROUND AND OBJECTIVES: Inflammasomes are involved in the pathogenesis of different neuroimmune and neurodegenerative diseases, including multiple sclerosis (MS). In a previous study by our group, the nucleotide-binding oligomerization domain, leucine-rich repeat receptor and pyrin-domain–contain...

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Detalles Bibliográficos
Autores principales: Malhotra, Sunny, Hurtado-Navarro, Laura, Pappolla, Agustin, Villar, Luisa M. M., Río, Jordi, Montalban, Xavier, Pelegrin, Pablo, Comabella, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042441/
https://www.ncbi.nlm.nih.gov/pubmed/36973075
http://dx.doi.org/10.1212/NXI.0000000000200100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042441/
https://www.ncbi.nlm.nih.gov/pubmed/36973075
http://dx.doi.org/10.1212/NXI.0000000000200100

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