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A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation

Transcription factors play a determining role in lineage commitment and cell differentiation. Interferon regulatory factor 8 (IRF8) is a lineage determining transcription factor in hematopoiesis and master regulator of dendritic cells (DC), an important immune cell for immunity and tolerance. IRF8 i...

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Detalles Bibliográficos
Autores principales: Xu, Huaming, Li, Zhijian, Kuo, Chao-Chung, Götz, Katrin, Look, Thomas, de Toledo, Marcelo AS, Seré, Kristin, Costa, Ivan G, Zenke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042546/
https://www.ncbi.nlm.nih.gov/pubmed/36916882
http://dx.doi.org/10.7554/eLife.83342