Cargando…
A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation
Transcription factors play a determining role in lineage commitment and cell differentiation. Interferon regulatory factor 8 (IRF8) is a lineage determining transcription factor in hematopoiesis and master regulator of dendritic cells (DC), an important immune cell for immunity and tolerance. IRF8 i...
Autores principales: | Xu, Huaming, Li, Zhijian, Kuo, Chao-Chung, Götz, Katrin, Look, Thomas, de Toledo, Marcelo AS, Seré, Kristin, Costa, Ivan G, Zenke, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042546/ https://www.ncbi.nlm.nih.gov/pubmed/36916882 http://dx.doi.org/10.7554/eLife.83342 |
Ejemplares similares
-
Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses
por: Webster, Brian, et al.
Publicado: (2018) -
Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses
por: Lee, Jihyung, et al.
Publicado: (2020) -
IRF4 haploinsufficiency in a family with Whipple’s disease
por: Guérin, Antoine, et al.
Publicado: (2018) -
SPOP targets the immune transcription factor IRF1 for proteasomal degradation
por: Schwartz, Irene, et al.
Publicado: (2023) -
TGFβ1 microenvironment determines dendritic cell development
por: Seré, Kristin, et al.
Publicado: (2013)