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Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells

Radiation-induced fibrosis is a common side effect of radiotherapy, which is the most common treatment for cancer. However, radiation also causes p53-mediated cell cycle arrest, prolonged expression of p21, and the development of senescence in normal cells that reside in irradiated tissues. Bone mar...

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Detalles Bibliográficos
Autores principales: Lee, Amy H., Ghosh, Deepraj, Koh, Ivy L., Dawson, Michelle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042705/
https://www.ncbi.nlm.nih.gov/pubmed/36842089
http://dx.doi.org/10.18632/aging.204539