Tiotropium Bromide Improves Neutrophilic Asthma by Recovering Histone Deacetylase 2 Activity

BACKGROUND: The value of tiotropium bromide (TIO) in neutrophilic asthma was meaningful in previous study. We hypothesized that TIO’s mechanism of action is associated with histone deacetylase 2 (HDAC2) activity, which is key for controlling the transcription of inflammatory cytokines and usually do...

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Detalles Bibliográficos
Autores principales: An, Tai Joon, Kim, Ji Hye, Hur, Jung, Park, Chan Kwon, Lim, Jeong Uk, Kim, Seohyun, Rhee, Chin Kook, Yoon, Hyoung Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042725/
https://www.ncbi.nlm.nih.gov/pubmed/36974400
http://dx.doi.org/10.3346/jkms.2023.38.e91

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042725/
https://www.ncbi.nlm.nih.gov/pubmed/36974400
http://dx.doi.org/10.3346/jkms.2023.38.e91

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