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Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway

Most tumor cells undergo apoptosis in circulation and at the metastatic organ sites due to host immune surveillance and a hostile microenvironment. It remains to be elucidated whether dying tumor cells have a direct effect on live tumor cells during the metastatic process and what the underlying mec...

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Detalles Bibliográficos
Autores principales: Park, Woo-Yong, Gray, Justin M., Holewinski, Ronald J., Andresson, Thorkell, So, Jae Young, Carmona-Rivera, Carmelo, Hollander, M. Christine, Yang, Howard H., Lee, Maxwell, Kaplan, Mariana J., Cappell, Steven D., Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042736/
https://www.ncbi.nlm.nih.gov/pubmed/36973439
http://dx.doi.org/10.1038/s43018-023-00524-z