Levosimendan increases the phosphorylation state of phospholamban in the isolated human atrium

Levosimendan (up to 10 µM) given alone failed to increase force of contraction in isolated electrically stimulated (1 Hz) left atrial (LA) preparations from wild-type mice. Only in the additional presence of 0.1 µM rolipram, an inhibitor of the activity of phosphodiesterase IV, levosimendan increase...

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Detalles Bibliográficos
Autores principales: Abella, Lina Maria Rayo, Hoffmann, Robert, Neumann, Joachim, Hofmann, Britt, Gergs, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042762/
https://www.ncbi.nlm.nih.gov/pubmed/36445386
http://dx.doi.org/10.1007/s00210-022-02348-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042762/
https://www.ncbi.nlm.nih.gov/pubmed/36445386
http://dx.doi.org/10.1007/s00210-022-02348-7

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