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Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air–liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells

ABSTRACT: The airway epithelium represents the main barrier between inhaled air and the tissues of the respiratory tract and is therefore an important point of contact with xenobiotic substances into the human body. Several studies have recently shown that in vitro models of the airway grown at an a...

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Detalles Bibliográficos
Autores principales: Djidrovski, Ivo, Georgiou, Maria, Tasinato, Elena, Leonard, Martin O., Van den Bor, Jelle, Lako, Majlinda, Armstrong, Lyle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042770/
https://www.ncbi.nlm.nih.gov/pubmed/35641671
http://dx.doi.org/10.1007/s10565-022-09726-0