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Theoretical and molecular mechanistic investigations of novel (3-(furan-2-yl)pyrazol-4-yl) chalcones against lung carcinoma cell line (A549)

A new chalcone series has been developed that may be useful in the treatment of lung cancer. The new series was confirmed by the different spectral tools. MTT assay was used to detect the cytotoxic effect of the novel chalcones against lung cancer cell line (A549). Molecular docking studies were per...

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Detalles Bibliográficos
Autores principales: Mohamed, Magda F., Ibrahim, Nada S., Saddiq, Amna A., Almaghrabi, Omar A., Al-Hazemi, Maha E., Hassaneen, Hamdi M., Abdelhamid, Ismail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042774/
https://www.ncbi.nlm.nih.gov/pubmed/36469109
http://dx.doi.org/10.1007/s00210-022-02344-x