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Cloning, characterization, and heterologous expression of a candidate Hirudin gene from the salivary gland transcriptome of Hirudo nipponia

Hirudin is a pharmacologically active substance in leeches with potent blood anticoagulation properties. Although recombinant hirudin production isolated from Hirudo medicinalis Linnaeus and Hirudinaria manillensis Lesson is known, to our knowledge, this study is the first to report recombinant hiru...

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Detalles Bibliográficos
Autores principales: Shi, Ping, Wei, Jian, You, Huajian, Chen, Shijiang, Tan, Fayin, Lu, Zenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042815/
https://www.ncbi.nlm.nih.gov/pubmed/36973525
http://dx.doi.org/10.1038/s41598-023-32303-2