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Cloning, characterization, and heterologous expression of a candidate Hirudin gene from the salivary gland transcriptome of Hirudo nipponia
Hirudin is a pharmacologically active substance in leeches with potent blood anticoagulation properties. Although recombinant hirudin production isolated from Hirudo medicinalis Linnaeus and Hirudinaria manillensis Lesson is known, to our knowledge, this study is the first to report recombinant hiru...
Autores principales: | Shi, Ping, Wei, Jian, You, Huajian, Chen, Shijiang, Tan, Fayin, Lu, Zenghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042815/ https://www.ncbi.nlm.nih.gov/pubmed/36973525 http://dx.doi.org/10.1038/s41598-023-32303-2 |
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