Repertoire of P-glycoprotein drug transporters in the zoonotic nematode Toxocara canis

Toxocara canis has a complex lifecycle including larval stages in the somatic tissue of dogs that tolerate macrocyclic lactones. In this study, we investigated T. canis permeability glycoproteins (P-gps, ABCB1) with a putative role in drug tolerance. Motility experiments demonstrated that while iver...

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Detalles Bibliográficos
Autores principales: Jesudoss Chelladurai, Jeba R. J., Martin, Katy A., Vardaxis, Pam, Reinemeyer, Craig, Vijayapalani, Paramasivan, Robertson, Alan P., Brewer, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042841/
https://www.ncbi.nlm.nih.gov/pubmed/36973306
http://dx.doi.org/10.1038/s41598-023-31556-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042841/
https://www.ncbi.nlm.nih.gov/pubmed/36973306
http://dx.doi.org/10.1038/s41598-023-31556-1

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