Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases

Bacterial pathogens have evolved intricate mechanisms to evade the human immune system, including the production of immunomodulatory enzymes. Streptococcus pyogenes serotypes secrete two multi-modular endo-β-N-acetylglucosaminidases, EndoS and EndoS2, that specifically deglycosylate the conserved N-...

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Detalles Bibliográficos
Autores principales: Trastoy, Beatriz, Du, Jonathan J., Cifuente, Javier O., Rudolph, Lorena, García-Alija, Mikel, Klontz, Erik H., Deredge, Daniel, Sultana, Nazneen, Huynh, Chau G., Flowers, Maria W., Li, Chao, Sastre, Diego E., Wang, Lai-Xi, Corzana, Francisco, Mallagaray, Alvaro, Sundberg, Eric J., Guerin, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042849/
https://www.ncbi.nlm.nih.gov/pubmed/36973249
http://dx.doi.org/10.1038/s41467-023-37215-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042849/
https://www.ncbi.nlm.nih.gov/pubmed/36973249
http://dx.doi.org/10.1038/s41467-023-37215-3

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