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Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
Bacterial pathogens have evolved intricate mechanisms to evade the human immune system, including the production of immunomodulatory enzymes. Streptococcus pyogenes serotypes secrete two multi-modular endo-β-N-acetylglucosaminidases, EndoS and EndoS2, that specifically deglycosylate the conserved N-...
Autores principales: | Trastoy, Beatriz, Du, Jonathan J., Cifuente, Javier O., Rudolph, Lorena, García-Alija, Mikel, Klontz, Erik H., Deredge, Daniel, Sultana, Nazneen, Huynh, Chau G., Flowers, Maria W., Li, Chao, Sastre, Diego E., Wang, Lai-Xi, Corzana, Francisco, Mallagaray, Alvaro, Sundberg, Eric J., Guerin, Marcelo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042849/ https://www.ncbi.nlm.nih.gov/pubmed/36973249 http://dx.doi.org/10.1038/s41467-023-37215-3 |
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