Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway

Hernandezine (Her) is a bisbenzylisoquinoline alkaloid extracted from the traditional Chinese herbal medicine Thalictrum glandulosissimum. Evidence shows that Her is a natural agonist of adenosine monophosphate (AMP)-activated protein kinase (AMPK) and induces apoptosis and autophagy in tumor cells....

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Detalles Bibliográficos
Autores principales: Song, Chang-feng, Hu, Yu-heng, Mang, Zhi-guo, Ye, Zeng, Chen, Hai-di, Jing, De-sheng, Fan, Gui-xiong, Ji, Shun-rong, Yu, Xian-jun, Xu, Xiao-wu, Qin, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042859/
https://www.ncbi.nlm.nih.gov/pubmed/36284209
http://dx.doi.org/10.1038/s41401-022-01006-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042859/
https://www.ncbi.nlm.nih.gov/pubmed/36284209
http://dx.doi.org/10.1038/s41401-022-01006-1

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