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Barnase-barstar Specific Interaction Regulates Car-T Cells Cytotoxic Activity toward Malignancy

The development of CAR-T specific therapy made a revolution in modern oncology. Despite the pronounced therapeutic effects, this novel approach displayed several crucial limitations caused by the complications in pharmacokinetics and pharmacodynamics controls. The presence of the several severe medi...

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Detalles Bibliográficos
Autores principales: Kalinin, R. S., Shipunova, V. O., Rubtsov, Y. P., Ukrainskay, V. M., Schulga, A., Konovalova, E. V., Volkov, D. V., Yaroshevich, I. A., Moysenovich, A. M., Belogurov, A. A., Telegin, G. B., Chernov, A. S., Maschan, M. A., Terekhov, S. S., Knorre, V. D., Khurs, E., Gnuchev, N. V., Gabibov, A. G., Deyev, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042900/
https://www.ncbi.nlm.nih.gov/pubmed/36653580
http://dx.doi.org/10.1134/S1607672922700041