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Barnase-barstar Specific Interaction Regulates Car-T Cells Cytotoxic Activity toward Malignancy
The development of CAR-T specific therapy made a revolution in modern oncology. Despite the pronounced therapeutic effects, this novel approach displayed several crucial limitations caused by the complications in pharmacokinetics and pharmacodynamics controls. The presence of the several severe medi...
Autores principales: | Kalinin, R. S., Shipunova, V. O., Rubtsov, Y. P., Ukrainskay, V. M., Schulga, A., Konovalova, E. V., Volkov, D. V., Yaroshevich, I. A., Moysenovich, A. M., Belogurov, A. A., Telegin, G. B., Chernov, A. S., Maschan, M. A., Terekhov, S. S., Knorre, V. D., Khurs, E., Gnuchev, N. V., Gabibov, A. G., Deyev, S. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pleiades Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042900/ https://www.ncbi.nlm.nih.gov/pubmed/36653580 http://dx.doi.org/10.1134/S1607672922700041 |
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