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Influence of Tyrosyl-DNA Phosphodiesterase 1 Inhibitor on the Proapoptotic and Genotoxic Effects of Anticancer Agent Topotecan

To date, various strategies have been proposed to increase the efficiency of cancer therapy. It is known that the action of DNA repair system can determine the resistance of cancer cells to DNA-damaging chemotherapy and radiotherapy, and one of these ways to increase therapeutic efficiency is the se...

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Detalles Bibliográficos
Autores principales: Chepanova, A. A., Zakharenko, A. L., Dyrkheeva, N. S., Chernyshova, I. A., Zakharova, O. D., Ilina, E. S., Luzina, O. A., Salakhutdinov, N. F., Lavrik, O. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042932/
https://www.ncbi.nlm.nih.gov/pubmed/36653585
http://dx.doi.org/10.1134/S1607672922700077