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Excessive iodine induces thyroid follicular epithelial cells apoptosis by activating HIF-1α-mediated hypoxia pathway in Hashimoto thyroiditis

BACKGROUND: Hashimoto thyroiditis (HT) is considered the most common autoimmune thyroid disease. A growing body of evidence suggests that HT incidence correlates with excessive iodine intake. We should probe the effects of excessive iodine intake in HT development and its possible mechanism. METHODS...

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Detalles Bibliográficos
Autores principales: Zhang, Lili, Sun, Xiaojing, Liu, Lin, Wang, Ping, Qian, Linxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042978/
https://www.ncbi.nlm.nih.gov/pubmed/36807042
http://dx.doi.org/10.1007/s11033-023-08273-z