Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro

Adverse outcome pathways (AOPs) are organized sequences of key events (KEs) that are triggered by a xenobiotic-induced molecular initiating event (MIE) and summit in an adverse outcome (AO) relevant to human or ecological health. The AOP framework causally connects toxicological mechanistic informat...

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Detalles Bibliográficos
Autores principales: Klose, Jördis, Li, Lu, Pahl, Melanie, Bendt, Farina, Hübenthal, Ulrike, Jüngst, Christian, Petzsch, Patrick, Schauss, Astrid, Köhrer, Karl, Leung, Ping Chung, Wang, Chi Chiu, Koch, Katharina, Tigges, Julia, Fan, Xiaohui, Fritsche, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042984/
https://www.ncbi.nlm.nih.gov/pubmed/35701726
http://dx.doi.org/10.1007/s10565-022-09730-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042984/
https://www.ncbi.nlm.nih.gov/pubmed/35701726
http://dx.doi.org/10.1007/s10565-022-09730-4

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